Linked Life Data

10148557

Source:http://linkedlifedata.com/resource/pubmed/id/10148557

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-8-26
pubmed:abstractText
We have evaluated the ability of ethylene oxide gas to penetrate bone matrices and subsequently kill a defined microbiological load. These experiments demonstrated that freeze-dried cancellous and cortical bone did not pose a barrier to the rapid diffusion of the gas. A normal cycle on a commercial ethylene oxide steriliser provided a sixfold overkill. Minor differences in the rate at which the microbiological load was killed (D-value) were seen between cortical and cancellous bone, processed and unprocessed bone, and bone of different thickness. These differences were negligible in comparison to the degree of overkill observed. Spore indicators placed freely in the steriliser chamber were shown to act as excellent monitors for the bone sterilisation process. Preliminary studies of ethylene oxide residuals indicated that processed, freeze-dried bone could be sterilised without leaving leachable toxic residuals in the matrix.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
T
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0267-6605
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
129-35
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Ethylene oxide sterilisation of allogenic bone implants.
pubmed:affiliation
Yorkshire Regional Tissue Bank, Pinderfields General Hospital, West Yorkshire, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't