Linked Life Data

1011169

Source:http://linkedlifedata.com/resource/pubmed/id/1011169

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1977-3-15
pubmed:abstractText
The influence on the growth of the presence of testosterone or estradiol at some stage of development was investigated from birth to adult age (90 days). 1. The presence of the androgenic molecule in the newborn organism, regardless of genetic sex (intact males, males orchidectomized at 9 days and neonatally injected orchidectomized males; neonatally injected intact and ovariectomized females), starts up a growth acceleration six weeks later. 2. The presence of the estrogenic molecule during this same period (neonatally injected intact and ovariectomized females; neonatally injected orchidectomized males) decreases the growth rate when animals come into puberty. 3. The development of the adult is immediately accelerated by androgen (excitatory effect) or reduced by estrogen (inhibitory effect). On the contrary, the effects of sex hormones present in the early postnatal period appear much later (inductive effect). Therefore, the activity patterns of sex hormones change with age: in the adult, androgen increases anabolism and estrogen decreases food intake; in the newborn, an undifferenciated mechanism responsible for growth is organized into "a male type" by androgen or "female type" by estrogen. The nature of this mechanism is discussed.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0021-7948
pubmed:author
pubmed:issnType
Print
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
567-78
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
[Induction in the newborn and maintenance in adulthood of a "male-type" growth or "female-type" growth depends on the nature of gonadic secretion (author's transl)].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract