Linked Life Data

10100497

Source:http://linkedlifedata.com/resource/pubmed/id/10100497

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-6-9
pubmed:abstractText
The changes in arterial pressure that follow withdrawal of a 3-h intravenous infusion of arginine vasopressin (AVP; 20 ng/kg/min) in spontaneously hypertensive rats (SHR) were monitored by radiotelemetry or conventional externalized femoral arterial catheters connected to pressure transducers. Baseline control arterial pressure was lower in the telemetry group compared to the externalized group. After withdrawal of the AVP infusion, blood pressure fell below preinfusion levels in both groups but the decrease was much less in the telemetry group. Strikingly, absolute blood pressure values recorded both during and after the vasopressin infusion were remarkably similar in the two groups. Responses in rats with externalized catheters implanted 7 days before infusion of AVP, a protocol similar to the telemetry group, were similar to those in rats with catheters implanted 24 h earlier. Blood pressure remained decreased in SHR infused with AVP for several days with complete recovery requiring 6-7 days. In contrast, physical activity decreased only on the first day following withdrawal of the infusion. Thus, the mechanism accounting for the blood pressure decrease must be of a long duration and unrelated to a change in gross physical activity. The results emphasize the value of radiotelemetry for recording blood pressure responses.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1056-8719
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
87-93
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Radiotelemetric versus externalized catheter monitoring of blood pressure: effect of vasopressin in spontaneous hypertension.
pubmed:affiliation
Department of Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Canada.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't