Linked Life Data

10098275

Source:http://linkedlifedata.com/resource/pubmed/id/10098275

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1999-5-6
pubmed:abstractText
The most effective mechanism for the elimination of disease from society is the use of vaccinations, but these often require repeated administration. However, single-administration vaccine formulations provide the repeated administrations automatically. One approach is the development of injectable controlled-release microsphere formulations containing the vaccine antigen that is released as a pulse 1-6 months after injection. The time of the pulse is dependent upon the rate of polymer degradation, which is dictated by the polymer's composition and molecular weight. This controlled-release technology may provide complete protection against disease after a single administration.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0167-7799
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
25-9
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Single-administration vaccines: controlled-release technology to mimic repeated immunizations.
pubmed:affiliation
Pharmaceutical R&D, Genentech, South San Francisco, CA 94080, USA. cleland@gene.com
pubmed:publicationType
Journal Article, Review