rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1999-6-22
|
pubmed:abstractText |
A capillary electrophoresis (CE) method was developed for the separation of a model hexapeptide (L-Val-L-Tyr-L-Pro-L-Asn-Gly-L-Ala) and its degradation products. Separations using CE had much shorter analysis times than the RP-HPLC assay used previously. CE was also evaluated for possible use in analyzing peptide samples containing polymers. With a thorough rinsing procedure between runs, the presence of a model polymer did not affect the separation of the peptides. The CE assay can be applied to the study of peptide stability in polymers.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0731-7085
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
421-7
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:10096836-Asparagine,
pubmed-meshheading:10096836-Chromatography, High Pressure Liquid,
pubmed-meshheading:10096836-Deamination,
pubmed-meshheading:10096836-Electrophoresis, Capillary,
pubmed-meshheading:10096836-Oligopeptides,
pubmed-meshheading:10096836-Peptide Fragments,
pubmed-meshheading:10096836-Peptides,
pubmed-meshheading:10096836-Polymers,
pubmed-meshheading:10096836-Polyvinyl Alcohol
|
pubmed:year |
1998
|
pubmed:articleTitle |
Capillary electrophoresis separation of an asparagine containing hexapeptide and its deamidation products.
|
pubmed:affiliation |
Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence 66047-2504, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|