Source:http://linkedlifedata.com/resource/pubmed/id/10091697
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1999-5-24
|
| pubmed:abstractText |
Synthesis of trans-fused lactones containing the indane nucleus has resulted in a series of potent acylating inhibitors of thrombin. As an example compound 11e has an apparent second order rate constant of 11 x 10(6) M(-1)sec(-1) for the inhibition of thrombin. The anticoagulant activity of these compounds is discussed.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0960-894X
|
| pubmed:author |
pubmed-author:BoltonR ERE,
pubmed-author:CooteS JSJ,
pubmed-author:FinchHH,
pubmed-author:HindleySS,
pubmed-author:LowdonAA,
pubmed-author:McDonaldEE,
pubmed-author:McLarenJJ,
pubmed-author:MooneyC JCJ,
pubmed-author:OwenMM,
pubmed-author:ParrySS,
pubmed-author:PassMM,
pubmed-author:PatelCC,
pubmed-author:PeggN ANA,
pubmed-author:TangC MCM
|
| pubmed:issnType |
Print
|
| pubmed:day |
8
|
| pubmed:volume |
9
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
431-6
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading | |
| pubmed:year |
1999
|
| pubmed:articleTitle |
Synthetic [5,5] trans-fused indane lactones as inhibitors of thrombin.
|
| pubmed:affiliation |
Glaxo Wellcome Research and Development, Stevenage, Herts, United Kingdom. mp8073@glaxowellcome.co.uk
|
| pubmed:publicationType |
Journal Article
|