Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1977-3-31
pubmed:abstractText
Local thrombosis was initiated in vivo by applying a weak electric current to the mesenteric artery of rats. The thrombi adhered to areas of arterial wall exhibiting endothelial cell loss and muscle cell damage. They showed no tendency to sustained growth and contained large amounts of vaguely fibrillary substance that enmeshed platelet aggregates and infiltrated the denuded subendothelial layer. The subsequent local administration of dilute ADP led to brisk platelet aggregation and rapid increase in size of the thrombi. The large thrombotic masses disappeared as soon as the administration of ADP was stopped, leaving behind small remnants which, like the initial thrombi, were predominantly composed of enmeshing substance and could be stimulated to renewed growth by resuming the administration of ADP. It appears that the enmeshing substance plays a major role in the stability and cohesion of early thrombi which do not yet contain fibrin. It conceivably is made up of fibrin monomers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0007-1021
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
722-32
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Thrombosis induced in vivo in the mesenteric artery of rats. An electron microscopic study of the initial phases.
pubmed:publicationType
Journal Article