Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-5-25
pubmed:abstractText
A synopsis of the many aspects and factors that contribute to renal tubulo-interstitial fibrosis is presented. The role of fibrogenic cytokines and the conversion of fibroblasts to myofibroblasts are described. It is emphasized that oxygen radicals cause fibroblasts to generate collagen. The properties of those accessory modulatory proteins that affect the behavior of cells in the interstitium are considered and how matrix for ensuing fibrosis is laid down. Understanding the extracellular matrix proteins and these modulatory proteins is important because their behavior can now be modified by means of antisense oligonucleotides.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0886-022X
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
121-33
pubmed:dateRevised
2008-5-21
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Modulatory proteins and processes in alliance with immune cells, mediators, and extracellular proteins in renal interstitial fibrosis.
pubmed:publicationType
Journal Article, Review