Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1999-4-15
pubmed:abstractText
A field trial was performed under commercial feedlot conditions in western Canada to compare the efficacy of florfenicol and tilmicosin for the treatment of undifferentiated fever (UF) in calves that received metaphylactic tilmicosin upon arrival at the feedlot. One thousand and eighty recently weaned, auction market derived, crossbred beef calves suffering from UF were allocated to one of 2 experimental groups as follows: florfenicol, which was intramuscular (i.m.) florfenicol administered at the rate of 20 mg/kg body weight (BW) at the time of allocation (Day 0) and again 48 h later, or tilmicosin, which was subcutaneous (s.c.) tilmicosin administered once at the rate of 10 mg/kg BW on day 0. Five hundred and forty-four animals were allocated to the florfenicol group and 536 animals were allocated to the tilmicosin group. The chronicity, wastage, overall mortality, and bovine respiratory disease (BRD) mortality rates were significantly (P < 0.05) lower in the florfenicol group than in the tilmicosin group. There were no significant (P > or = 0.05) differences in first UF relapse, second UF relapse, hemophilosis mortality, or miscellaneous mortality rates between the florfenicol and tilmicosin groups. Average daily gain (ADG) from arrival at the feedlot to the time of implanting and ADG from allocation to the time of implanting were significantly (P < 0.05) lower in the florfenicol group as compared with the tilmicosin group. There were no significant (P > or = 0.05) differences in arrival weight, allocation weight, implanting weight, or ADG from arrival to allocation between the experimental groups. In the economic analysis, there was an advantage of $18.83 CDN per animal in the florfenicol group. The results of this study indicate that florfenicol is superior to tilmicosin for the treatment of UF because of lower chronicity, wastage, overall mortality, and BRD mortality rates. However, interpretation of these observations must take into consideration the fact that these calves received meta-phylactic tilmicosin upon arrival at the feedlot, which is a standard, cost-effective, management procedure utilized by feedlots in western Canada.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-17422726, http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-17423045, http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-17423706, http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-17423754, http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-17423983, http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-17424022, http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-17424339, http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-1926728, http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-3434919, http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-7225993, http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-8428833, http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-9285135, http://linkedlifedata.com/resource/pubmed/commentcorrection/10086218-9524721
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0008-5286
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
179-84
pubmed:dateRevised
2010-9-14
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
A comparison of florfenicol and tilmicosin for the treatment of undifferentiated fever in feedlot calves in western Canada.
pubmed:affiliation
Feedlot Health Management Services, Okotoks, Alberta.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't