Linked Life Data

10085471

Source:http://linkedlifedata.com/resource/pubmed/id/10085471

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1999-5-17
pubmed:abstractText
At a single evening dose of 5-10 mg, melatonin (MLT), the pineal gland hormone, can exert a positive effect on the frequency of epileptic attacks in children with sleep disturbances of various etiologies. We have shown that the sleep behavior can be normalized and an existing epilepsy can be favorably influenced. Pretherapeutic MLT secretion profiles can provide new information concerning the origin and treatment of these disturbances. In vitro experiments suggest that this effect might be the result of the interaction between MLT and MLT-specific receptors in the neocortex. Due to its favorable safety profile, MLT can be liberally administered in the specified doses and be considered as a useful antiepileptic drug.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1422-4933
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
105-10
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Melatonin in epilepsy: first results of replacement therapy and first clinical results.
pubmed:affiliation
Jenapharm GmbH & Co. KG, Jena, Germany.Jandirk.fauteck@schering.de
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't