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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1978-12-27
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pubmed:abstractText |
Bioassay methods for actinomycin D, 6-thioguanine, and adriamycin which utilize laser light scattering from suspensions of drug-sensitive bacteria have been developed. In 3 hours, serum and urine levels of the 3 drugs can be reproducibily measured. A sample volume of 0.1 ml may be assayed with a precision of +/- 10%. The linear response range for actinomycin D was 0.03 to 3.0 microgram/ml. For 6-thioguanine and adriamycin the linear responses range was 0.03 to 10.0 and 0.25 to 10.0 microgram/ml, respectively. Thetively. The present studies further confirm the general utility of differential light scattering as a rapid and inexpensive assay procedure of broad application.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
pubmed:issn |
0034-5164
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
531-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:100836-Antineoplastic Agents,
pubmed-meshheading:100836-Biological Assay,
pubmed-meshheading:100836-Dactinomycin,
pubmed-meshheading:100836-Diffusion,
pubmed-meshheading:100836-Doxorubicin,
pubmed-meshheading:100836-Enterococcus faecalis,
pubmed-meshheading:100836-Lasers,
pubmed-meshheading:100836-Nephelometry and Turbidimetry,
pubmed-meshheading:100836-Thioguanine
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pubmed:year |
1978
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pubmed:articleTitle |
Laser differential light scattering bioassays for selected antitumor agents.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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