Linked Life Data

10082278

Source:http://linkedlifedata.com/resource/pubmed/id/10082278

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1999-4-27
pubmed:abstractText
Tympanic membrane (TM) stiffness changes in the pars tensa in response to experimentally induced ear canal cholesteatoma by obstruction of the ear canal were studied. To this aim TM displacement versus pressure was measured with a high resolution, differential moiré interferometer. The measurements were performed on fresh, isolated gerbil temporal bones after removal of the cholesteatoma bulk. Besides an overall stiffness reduction we found that local stiffness variations were present in nine out of 18 studied ears. The stiffness changes as a function of time after ear canal obstruction had a pattern similar to those previously shown to develop in response to various forms of otitis media, showing that the TM stiffness properties decrease in a similar way in response to different inflammatory middle ear diseases. The stiffness changes correlated with an increased overall TM thickness and increased thickness of the lamina propria in particular as measured in histology sections. The stiffness changes may play an important role in the pathophysiology of cholesteatoma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0378-5955
pubmed:author
pubmed:issnType
Print
pubmed:volume
128
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-15
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Tympanic membrane displacement patterns in experimental cholesteatoma.
pubmed:affiliation
The Department of Otorhinolaryngology, Karolinska Hospital and Karolinska Institute, Stockholm, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't