Linked Life Data

10081994

Source:http://linkedlifedata.com/resource/pubmed/id/10081994

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-4-29
pubmed:abstractText
Extracellular fluid and closely related extracellular water (ECW) provide information on nutritional status in health and disease. Although various methods exist for ECW determination, little is known about their comparability in patients with wasting diseases such as acquired immunodeficiency syndrome (AIDS). One practical method, the dilution of sodium bromide (NaBr), is used widely in clinical research, although its relationship to other ECW markers has not been well characterized. The present study sought to compare ECW estimates as determined by NaBr and three other methods in 11 male patients with AIDS (mean +/- SD; age, 44+/-12 years; body weight, 64.5+/-8.8 kg; and height, 172+/-4 cm). ECW volumes were determined from NaBr dilution, total body chlorine (TBCl) by delayed gamma-neutron activation analysis, total body water (TBW) by tritium dilution combined with total body potassium (TBK) by whole body 40K counting, and radioactive sulfate dilution (35SO4). All correlations between the NaBr method and other methods were statistically significant (NaBr vs TBCl [r = .91; p < .001]; vs TBW/TBK [r = .76; p < .01]; and vs 35SO4 [r = .89; p < .001]). As expected from previous studies, ECW (L) derived by NaBr provided a group mean (15.1+/-2.2 L) similar to the TBCl method (15.4+/-1.7 L; p = .32), a significantly smaller ECW than by the TBW/TBK method (18.6+/-3.4 L; p = .0004), and a significantly larger ECW than by 35SO4 method (13.3+/-3.0 L; p = .002). Estimating ECW by NaBr dilution was comparable with other research-based ECW methods and, thus, offers a practical alternative for evaluating ECW in patients with AIDS.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0148-6071
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61-6
pubmed:dateRevised
2007-2-21
pubmed:meshHeading
pubmed-meshheading:10081994-Acquired Immunodeficiency Syndrome, pubmed-meshheading:10081994-Adult, pubmed-meshheading:10081994-Body Mass Index, pubmed-meshheading:10081994-Body Water, pubmed-meshheading:10081994-Bromides, pubmed-meshheading:10081994-Chlorine, pubmed-meshheading:10081994-Extracellular Space, pubmed-meshheading:10081994-Humans, pubmed-meshheading:10081994-Indicator Dilution Techniques, pubmed-meshheading:10081994-Male, pubmed-meshheading:10081994-Middle Aged, pubmed-meshheading:10081994-Neutron Activation Analysis, pubmed-meshheading:10081994-Potassium, pubmed-meshheading:10081994-Potassium Radioisotopes, pubmed-meshheading:10081994-Serum Albumin, pubmed-meshheading:10081994-Sodium, pubmed-meshheading:10081994-Sodium Compounds, pubmed-meshheading:10081994-Sulfates, pubmed-meshheading:10081994-Sulfur Radioisotopes, pubmed-meshheading:10081994-Tritium
pubmed:articleTitle
Extracellular water: sodium bromide dilution estimates compared with other markers in patients with acquired immunodeficiency syndrome.
pubmed:affiliation
Obesity Research Center and Body Composition Unit, St Luke's/Roosevelt Hospital, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
pubmed:publicationType
Journal Article, Comparative Study