Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1999-7-7
pubmed:abstractText
The 1993 outbreak of hantavirus pulmonary syndrome (HPS) in the southwestern United States was associated with Sin Nombre virus, a rodent-borne hantavirus; The virus' primary reservoir is the deer mouse (Peromyscus maniculatus). Hantavirus-infected rodents were identified in various regions of North America. An extensive nucleotide sequence database of an 139 bp fragment amplified from virus M genomic segments was generated. Phylogenetic analysis confirmed that SNV-like hantaviruses are widely distributed in Peromyscus species rodents throughout North America. Classic SNV is the major cause of HPS in North America, but other Peromyscine-borne hantaviruses, e.g., New York and Monongahela viruses, are also associated with HPS cases. Although genetically diverse, SNV-like viruses have slowly coevolved with their rodent hosts. We show that the genetic relationships of hantaviruses in the Americas are complex, most likely as a result of the rapid radiation and speciation of New World sigmodontine rodents and occasional virus-host switching events.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-1840609, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-2861241, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-7494337, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-7544047, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-7853545, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-7941323, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-8084007, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-8178455, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-8235615, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-8678841, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-8712893, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-9025697, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-9204290, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-9375015, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-9420200, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-9498614, http://linkedlifedata.com/resource/pubmed/commentcorrection/10081674-9574803
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1080-6040
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
75-86
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:articleTitle
Genetic diversity and distribution of Peromyscus-borne hantaviruses in North America.
pubmed:affiliation
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
pubmed:publicationType
Journal Article