Source:http://linkedlifedata.com/resource/pubmed/id/10077728
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1999-5-21
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pubmed:abstractText |
Alopecia areata is a common skin disease in which proinflammatory cytokines such as IL-1beta may play a pathogenic role. In this study, we examined the distribution of genotypes of an IL-1beta single base change polymorphism at position +3953 in patients with alopecia areata. The distribution of immunoglobulin kappa light chain (KM) genotypes was similarly examined. The data obtained showed that the IL-1beta and KM loci act cooperatively to significantly increase susceptibility to alopecia areata.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0001-5652
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
85-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10077728-Adolescent,
pubmed-meshheading:10077728-Adult,
pubmed-meshheading:10077728-Alopecia Areata,
pubmed-meshheading:10077728-Child,
pubmed-meshheading:10077728-Chromosomes, Human, Pair 2,
pubmed-meshheading:10077728-Genotype,
pubmed-meshheading:10077728-Heterozygote,
pubmed-meshheading:10077728-Homozygote,
pubmed-meshheading:10077728-Humans,
pubmed-meshheading:10077728-Immunoglobulin kappa-Chains,
pubmed-meshheading:10077728-Interleukin-1,
pubmed-meshheading:10077728-Polymorphism, Genetic
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pubmed:year |
1999
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pubmed:articleTitle |
Contribution of interleukin 1beta and KM loci to alopecia areata.
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pubmed:affiliation |
Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425-2230, USA.galbragm@musc.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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