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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11-12
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pubmed:dateCreated |
1977-2-24
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pubmed:abstractText |
In 6-sulfanilamidoindazole (6-SAI) arthritis the total haemolytic complement activity of the serum was significantly increased by 69% in developing arthritis at day 4, and by 42% in fully developed arthritis at day 8. In declining arthritis at day 12, 5 days after the last administration of the prophlogistic agent 6-SAI, no difference of the serum complement activity between arthritic rats and non-arthritic controls could be determined. The serum SH group concentration was significantly decreased by 31% at day 4 and by 54% at day 8, but it was nearly normalized at day 12. There was no close correlation between increase of paw diameter and serum complement activity in 6-SAI-arthritic rats. It is suggested that investigations on the role that complement components might play in 6-SAI arthritis could be interest.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Complement System Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Indazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfanilamides,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfhydryl Compounds
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pubmed:status |
MEDLINE
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pubmed:issn |
0340-1855
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
403-6
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:1007637-Animals,
pubmed-meshheading:1007637-Arthritis, Experimental,
pubmed-meshheading:1007637-Complement System Proteins,
pubmed-meshheading:1007637-Indazoles,
pubmed-meshheading:1007637-Male,
pubmed-meshheading:1007637-Periarthritis,
pubmed-meshheading:1007637-Pyrazoles,
pubmed-meshheading:1007637-Rats,
pubmed-meshheading:1007637-Sulfanilamides,
pubmed-meshheading:1007637-Sulfhydryl Compounds
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pubmed:articleTitle |
6-Sulfanilamidoindazole arthritis of the rat: complement activity and sulfhydryl group concentration of the serum in three different phases of inflammation.
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pubmed:publicationType |
Journal Article
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