Linked Life Data

10073815

Source:http://linkedlifedata.com/resource/pubmed/id/10073815

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-4-7
pubmed:abstractText
The presenting electrocardiogram may contain information indicating the probability of successful reperfusion. The relation between 3 parameters in the presenting electrocardiogram (pathologic Q waves, T-wave inversion, and the slope of ST elevation) and Thrombolysis in Myocardial Infarction trial (TIMI) grade 3 flow in the infarct-related artery was assessed angiographically 90 minutes after beginning streptokinase in 362 patients. TIMI grade 3 flow was more common in patients without Q waves (55%) than in those with Q waves (35%; p <0.001), and more common in patients without T-wave inversion (50%) than in those with T-wave inversion (30%; p <0.002). There was no relation between the slope of the ST segment or the magnitude of its deviation and the achievement of TIMI grade 3 flow. Only 20% of the 59 patients with both Q waves and T-wave inversion had TIMI grade 3 flow, compared with 50% of the remaining patients (p <0.0001). Among patients treated within 3 hours, TIMI grade 3 flow was seen in 68% of those without versus 44% of those with Q waves (p <0.01), and in 62% of those without versus 43% of those with T-wave inversion (p = 0.06). Among patients treated after 3 hours, TIMI grade 3 flow was seen in 38% of those without versus 30% of those with Q waves (p = NS), and in 38% of those without versus 23% of those with T-wave inversion (p <0.05). On multivariate analysis, the absence of Q waves, the time from the onset of chest pain to treatment, and age were independent predictors of TIMI grade 3 flow. Pathologic Q waves in the presenting electrocardiogram provide valuable information as to the probability of achieving successful reperfusion following administration of streptokinase, and may be helpful for triage of patients to alternative reperfusion strategies, including percutaneous revascularization.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
164-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:10073815-Anticoagulants, pubmed-meshheading:10073815-Cohort Studies, pubmed-meshheading:10073815-Coronary Angiography, pubmed-meshheading:10073815-Electrocardiography, pubmed-meshheading:10073815-Female, pubmed-meshheading:10073815-Fibrinolytic Agents, pubmed-meshheading:10073815-Hirudin Therapy, pubmed-meshheading:10073815-Hirudins, pubmed-meshheading:10073815-Humans, pubmed-meshheading:10073815-Logistic Models, pubmed-meshheading:10073815-Male, pubmed-meshheading:10073815-Middle Aged, pubmed-meshheading:10073815-Myocardial Infarction, pubmed-meshheading:10073815-Myocardial Reperfusion, pubmed-meshheading:10073815-Peptide Fragments, pubmed-meshheading:10073815-Predictive Value of Tests, pubmed-meshheading:10073815-Recombinant Proteins, pubmed-meshheading:10073815-Streptokinase
pubmed:year
1999
pubmed:articleTitle
Usefulness of the presenting electrocardiogram in predicting successful reperfusion with streptokinase in acute myocardial infarction.
pubmed:affiliation
Cardiovascular Research Unit, Green Lane Hospital, Auckland, New Zealand.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study