Linked Life Data

10072645

Source:http://linkedlifedata.com/resource/pubmed/id/10072645

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1999-5-19
pubmed:abstractText
The ductus arteriosus in the fetus may contract after administration of nonsteroidal anti-inflammatory drugs such as indomethacin and aspirin. We report a similar effect observed after a 36-week pregnant women was given diclofenac against flank pains. The ductus of this fetus was vasoconstricted with evidence of right ventricular hypertension. It resolved after cessation of the drug. Diclofenac is a cyclo-oxygenase inhibitor and thus carries the pharmacodynamic properties of other nonsteroidal anti-inflammatory drugs with inhibition of prostaglandin synthesis, resulting in vasoconstriction of the ductus arteriosus. We suggest monitoring of the fetal ductus state and velocities by fetal echocardiography in women treated with diclofenac.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1015-3837
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
24-5
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Contraction of the fetal ductus arteriosus induced by diclofenac. Case report.
pubmed:affiliation
Division of Pediatric Cardiology, Hadassah University Hospital, Jerusalem, Israel. rein@cc.huji.ac.il
pubmed:publicationType
Journal Article