Source:http://linkedlifedata.com/resource/pubmed/id/10072029
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1999-3-25
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pubmed:abstractText |
Postanesthetic shivering (PS) is distressing for patients and may induce a variety of complications. In this prospective, double-blinded, randomized study, we evaluated the value of nalbuphine, compared with meperidine and saline, for treating PS. Ninety adult patients were included in the study. Group 1 (n = 30) received i.v. nalbuphine 0.08 mg/kg, Group 2 (n = 30) received i.v. meperidine 0.4 mg/kg, and Group 3 (n = 30) received i.v. saline. Treatment that stopped shivering was considered to have been successful. The results demonstrated that, 5 min after treatment, both nalbuphine and meperidine provided a rapid and potent anti-shivering effect on PS, with high response rates of 80% and 83%, compared with those of saline (0%) (P < 0.01). Thirty minutes after injection, the response rates of nalbuphine and meperidine were 90% and 93%, respectively, compared with 17% in the saline group (P < 0.01). The differences between nalbuphine and meperidine were not significant. We conclude that nalbuphine may be an alternative to meperidine for treating PS. IMPLICATIONS: We evaluated nalbuphine versus meperidine and saline for treating postanesthetic shivering. Our results demonstrate that both nalbuphine and meperidine provide a similar rapid and potent anti-shivering effect. Nalbuphine may be an alternative to meperidine for treating postanesthetic shivering.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Analgesics, Opioid,
http://linkedlifedata.com/resource/pubmed/chemical/Meperidine,
http://linkedlifedata.com/resource/pubmed/chemical/Nalbuphine,
http://linkedlifedata.com/resource/pubmed/chemical/Narcotic Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Placebos
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0003-2999
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
686-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10072029-Adult,
pubmed-meshheading:10072029-Analgesics, Opioid,
pubmed-meshheading:10072029-Anesthesia, General,
pubmed-meshheading:10072029-Body Temperature,
pubmed-meshheading:10072029-Double-Blind Method,
pubmed-meshheading:10072029-Female,
pubmed-meshheading:10072029-Humans,
pubmed-meshheading:10072029-Male,
pubmed-meshheading:10072029-Meperidine,
pubmed-meshheading:10072029-Nalbuphine,
pubmed-meshheading:10072029-Narcotic Antagonists,
pubmed-meshheading:10072029-Placebos,
pubmed-meshheading:10072029-Prospective Studies,
pubmed-meshheading:10072029-Shivering
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pubmed:year |
1999
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pubmed:articleTitle |
A comparison among nalbuphine, meperidine, and placebo for treating postanesthetic shivering.
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pubmed:affiliation |
Department of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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