rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1999-3-10
|
pubmed:abstractText |
Muscarinic agents reduce intraocular pressure by enhancing aqueous outflow, probably by stimulating ciliary muscle contraction. However, pilocarpine is a well characterized neurotoxin and is widely used to generate animal seizure models. It was therefore investigated whether pilocarpine was also toxic to retinal ganglion cells.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0146-0404
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
40
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
813-6
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:10067991-Animals,
pubmed-meshheading:10067991-Cell Survival,
pubmed-meshheading:10067991-Cells, Cultured,
pubmed-meshheading:10067991-Dose-Response Relationship, Drug,
pubmed-meshheading:10067991-Drug Synergism,
pubmed-meshheading:10067991-Inositol,
pubmed-meshheading:10067991-Lithium,
pubmed-meshheading:10067991-Pilocarpine,
pubmed-meshheading:10067991-Rats,
pubmed-meshheading:10067991-Rats, Long-Evans,
pubmed-meshheading:10067991-Retinal Ganglion Cells
|
pubmed:year |
1999
|
pubmed:articleTitle |
Pilocarpine toxicity in retinal ganglion cells.
|
pubmed:affiliation |
The Department of Ophthalmology, Veterans Administration, and the University of Pennsylvania, Philadelphia 19104, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|