Source:http://linkedlifedata.com/resource/pubmed/id/10066705
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1999-5-7
|
| pubmed:abstractText |
Nine African and eight Caucasian 10-km runners resident at sea level volunteered. Maximal O2 consumption and peak treadmill velocity (PTV) were measured by using a progressive test, and fatigue resistance [time to fatigue (TTF)] was measured by using a newly developed high-intensity running test: 5 min at 72, 80, and 88% of individual PTV followed by 92% PTV to exhaustion. Skeletal muscle enzyme activities were determined in 12 runners and 12 sedentary control subjects. In a comparison of African and Caucasian runners, mean 10-km race time, maximal O2 consumption, and PTV were similar. In African runners, TTF was 21% longer (P < 0.01), plasma lactate accumulation after 5 min at 88% PTV was 38% lower (P < 0.05), and citrate synthase activity was 50% higher (27.9 +/- 7.5 vs. 18.6 +/- 2.1 micromol. g wet wt-1. min-1, P = 0.02). Africans accumulated lactate at a slower rate with increasing exercise intensity (P < 0.05). Among the entire group of runners, a higher citrate synthase activity was associated with a longer TTF (r = 0.70, P < 0.05), a lower plasma lactate accumulation (r = -0.73, P = 0.01), and a lower respiratory exchange ratio (r = -0.63, P < 0.05). We conclude that the African and Caucasian runners in the present study differed with respect to oxidative enzyme activity, rate of lactate accumulation, and their ability to sustain high-intensity endurance exercise.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
8750-7587
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
86
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
915-23
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:10066705-Adolescent,
pubmed-meshheading:10066705-Adult,
pubmed-meshheading:10066705-African Continental Ancestry Group,
pubmed-meshheading:10066705-Anaerobic Threshold,
pubmed-meshheading:10066705-Body Composition,
pubmed-meshheading:10066705-Body Height,
pubmed-meshheading:10066705-Body Weight,
pubmed-meshheading:10066705-Citrate (si)-Synthase,
pubmed-meshheading:10066705-European Continental Ancestry Group,
pubmed-meshheading:10066705-Humans,
pubmed-meshheading:10066705-Kinetics,
pubmed-meshheading:10066705-Lactic Acid,
pubmed-meshheading:10066705-Male,
pubmed-meshheading:10066705-Muscle, Skeletal,
pubmed-meshheading:10066705-Muscle Fatigue,
pubmed-meshheading:10066705-Muscle Fibers, Skeletal,
pubmed-meshheading:10066705-Oxygen Consumption,
pubmed-meshheading:10066705-Running
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
African runners exhibit greater fatigue resistance, lower lactate accumulation, and higher oxidative enzyme activity.
|
| pubmed:affiliation |
Medical Research Council/University of Cape Town Bioenergetics of Exercise Research Unit, Department of Physiology, Cape Town 7925, South Africa. A.Weston@cchs.usyd.edu.au
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, Non-U.S. Gov't
|