Recent research has brought additional information on how virus products interfere with host cell antigen processing in vitro, new information on the interaction of virus with dendritic cells as a mechanism for alteration of immune responses - especially immunosuppression, and a preliminary proposal that nonretroviral RNA viruses might persist by utilizing host-cell reverse transcriptase to enter a DNA phase of replication.
Division of Virology, Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. mbaobo@scripps.edu