Source:http://linkedlifedata.com/resource/pubmed/id/10052630
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1999-5-18
|
| pubmed:abstractText |
The conformation of the C-terminal octapeptide fragment of Substance P (SP4-11, Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2) has been investigated by 2D-NMR and MD methods. The octapeptide exists in a blend of conformations. The molecule seems to shuttle between conformations with gamma-bends either at Phe5 or Gly6 or Gln3 or Leu7 and between a nearly extended structure.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0739-1102
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
16
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
747-55
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:10052630-Animals,
pubmed-meshheading:10052630-Computer Simulation,
pubmed-meshheading:10052630-Magnetic Resonance Spectroscopy,
pubmed-meshheading:10052630-Models, Molecular,
pubmed-meshheading:10052630-Molecular Conformation,
pubmed-meshheading:10052630-Substance P,
pubmed-meshheading:10052630-Tachykinins,
pubmed-meshheading:10052630-Temperature
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
NMR and molecular dynamics studies of tachykinins: conformation of substance P fragment 4-11.
|
| pubmed:affiliation |
Bombay College of Pharmacy, Kalina, Mumbai, India.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|