Source:http://linkedlifedata.com/resource/pubmed/id/10052555
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1999-7-13
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pubmed:abstractText |
Twelve strains of methicillin-resistant Staphylococcus aureus with high-level resistance to mupirocin were studied. The MIC of methicillin was 16 to 128 mg/l and the MIC of mupirocin > or = 512 mg/l. All of the isolates carried a plasmid of about 30 MDa, and one strain lost resistance to mupirocin when the plasmid was cured. Three different resistance patterns were found: six strains were resistant to ciprofloxacin, kanamycin, and 10 mg/l of cadmium sulfate; two strains were resistant to these agents as well as to gentamicin, erythromycin, clindamycin, mercury chloride, and ethidium bromide; and four strains were resistant to the previously named agents as well as to rifampicin and tetracycline. The use of this valuable topical antibiotic, especially in long-term-care facilities, should be monitored to avoid dissemination of resistance.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0934-9723
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
877-9
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pubmed:dateRevised |
2006-5-1
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pubmed:meshHeading |
pubmed-meshheading:10052555-Anti-Bacterial Agents,
pubmed-meshheading:10052555-Drug Resistance, Microbial,
pubmed-meshheading:10052555-Humans,
pubmed-meshheading:10052555-Methicillin Resistance,
pubmed-meshheading:10052555-Microbial Sensitivity Tests,
pubmed-meshheading:10052555-Mupirocin,
pubmed-meshheading:10052555-Plasmids,
pubmed-meshheading:10052555-Spain,
pubmed-meshheading:10052555-Staphylococcal Infections,
pubmed-meshheading:10052555-Staphylococcus aureus
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pubmed:year |
1998
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pubmed:articleTitle |
High-level mupirocin resistance among Spanish methicillin-resistant Staphylococcus aureus.
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pubmed:affiliation |
Department of Microbiology, Hospital Universitario de la Princesa, Madrid, Spain. microbiologia@hup.es
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pubmed:publicationType |
Journal Article
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