Linked Life Data

10051361

Source:http://linkedlifedata.com/resource/pubmed/id/10051361

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-5-11
pubmed:abstractText
The hypothesis that growth hormesis represents an overcompensation to a disruption in homeostasis was supported in experiments assessing the effects of the synthetic plant growth inhibitor phosfon (2,4-dichlorobenzyl tributyl phosphonium chloride) on peppermint. While dose-dependent decreases in growth occurred initially in all treatment groups substantial compensation growth subsequently occurred across treatment groups. The low-dose treatment groups more than fully compensated for the initial growth decrement (20-25%), displaying a net stimulatory response by 5 weeks, whereas the high-dose treatment groups never fully compensated for the initial growth decrement (50-75%). These findings, within the context of other similar reported observations, are believed to be widely generalizable and may have important implications for biomedical fields including the design and interpretation of the bioassay especially within the context of the hazard/risk assessment process.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0147-6513
pubmed:author
pubmed:copyrightInfo
Copyright 1999 Academic Press.
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
135-7
pubmed:dateRevised
2000-12-18
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Evidence that hormesis represents an "overcompensation" response to a disruption in homeostasis.
pubmed:affiliation
School of Public Health, University of Massachusetts, Amherst, Massachusetts, 01003, USA.
pubmed:publicationType
Journal Article