rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1999-5-28
|
pubmed:abstractText |
Skin eruptions have been reported with the use of all antiepileptic drugs and there is a significant risk of cross-reactivity between these agents in causing serious eruptions such as Stevens-Johnson's syndrome. Gabepentin is usually considered a safe agent for patients with a previous history of drug allergies and there have been no cases of skin eruption reported to the gabapentin post marketing surveillance. We report a patient who had severe Stevens-Johnson's syndrome induced by phenytoin and later by carbamazepine. Subsequent use of gabapentin also resulted in a skin eruption which was limited to the lower extremities but without systemic or mucosal involvement. This case suggests that patients with a strong history of drug-induced idiosyncratic reactions may experience such reactions to gabapentin as well.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0163-4356
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
137-8
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:10051068-Acetic Acids,
pubmed-meshheading:10051068-Adult,
pubmed-meshheading:10051068-Amines,
pubmed-meshheading:10051068-Anticonvulsants,
pubmed-meshheading:10051068-Cyclohexanecarboxylic Acids,
pubmed-meshheading:10051068-Drug Hypersensitivity,
pubmed-meshheading:10051068-Female,
pubmed-meshheading:10051068-Humans,
pubmed-meshheading:10051068-Skin Diseases,
pubmed-meshheading:10051068-Stevens-Johnson Syndrome,
pubmed-meshheading:10051068-gamma-Aminobutyric Acid
|
pubmed:year |
1999
|
pubmed:articleTitle |
Skin eruption with gabapentin in a patient with repeated AED-induced Stevens-Johnson's syndrome.
|
pubmed:affiliation |
Department of Neurology, University of Miami, Florida 33136, USA.
|
pubmed:publicationType |
Journal Article,
Case Reports
|