|
rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
3
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pubmed:dateCreated |
1999-6-22
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|
pubmed:abstractText |
Six patients with uncomplicated falciparum malaria received artesunate for 5 days. Plasma concentrations of artesunate and dihydroartemisinin were determined by high-performance liquid chromatography with electrochemical detection. The concentrations of dihydroartemisinin in plasma 2 h after a dose showed a time-dependent decline. Concentrations of artesunate in plasma especially after the last dose, were very low. Despite this, all patients responded with a fast recovery.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0066-4804
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
43
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
690-2
|
|
pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:10049291-Adult,
pubmed-meshheading:10049291-Antimalarials,
pubmed-meshheading:10049291-Artemisinins,
pubmed-meshheading:10049291-Chromatography, High Pressure Liquid,
pubmed-meshheading:10049291-Electrochemistry,
pubmed-meshheading:10049291-Humans,
pubmed-meshheading:10049291-Malaria, Falciparum,
pubmed-meshheading:10049291-Male,
pubmed-meshheading:10049291-Sesquiterpenes
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|
pubmed:year |
1999
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|
pubmed:articleTitle |
Declining concentrations of dihydroartemisinin in plasma during 5-day oral treatment with artesunate for Falciparum malaria.
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|
pubmed:affiliation |
Institute for Clinical Research in Tropical Medicine, Bach Mai Hospital, Hanoi, Vietnam.
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|
pubmed:publicationType |
Journal Article,
Clinical Trial
|
