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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1999-4-27
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pubmed:abstractText |
Sox proteins belong to the HMG box superfamily of DNA-binding proteins and are found throughout the animal kingdom. They are involved in the regulation of such diverse developmental processes as germ layer formation, organ development and cell type specifi-cation. Hence, deletion or mutation of Sox proteins often results in developmental defects and congenital disease in humans. Sox proteins perform their function in a complex interplay with other transcription factors in a manner highly dependent on cell type and promoter context. They exhibit a remarkable crosstalk and functional redundancy among each other.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0305-1048
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1409-20
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pubmed:dateRevised |
2008-11-20
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pubmed:meshHeading |
pubmed-meshheading:10037800-DNA-Binding Proteins,
pubmed-meshheading:10037800-Gene Expression Regulation, Developmental,
pubmed-meshheading:10037800-High Mobility Group Proteins,
pubmed-meshheading:10037800-Lens, Crystalline,
pubmed-meshheading:10037800-Nervous System,
pubmed-meshheading:10037800-Nuclear Proteins,
pubmed-meshheading:10037800-Sex Differentiation,
pubmed-meshheading:10037800-Sex-Determining Region Y Protein,
pubmed-meshheading:10037800-Transcription Factors
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pubmed:year |
1999
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pubmed:articleTitle |
From head to toes: the multiple facets of Sox proteins.
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pubmed:affiliation |
Zentrum für Molekulare Neurobiologie, Universität Hamburg, Martinistrasse 52, D-20246 Hamburg, Germany. wegner@uke.uni-hamburg.de
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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