Source:http://linkedlifedata.com/resource/pubmed/id/10037301
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1999-3-5
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pubmed:abstractText |
Recent advances in molecular oncology have provided explanations at the DNA level for the malignant transformation and metastatic potential of various cancers. Malignant melanoma and pancreatic cancer may be classified together in both these cancers exhibit mutations in, or loss of, the cell-cycle inhibitory gene, p16. This paper reviews the current literature on p16 expression in melanoma and pancreatic cancer, explores factors that place patients with these cancers in categories of high risk for metastases or recurrence, and addresses whether aberrant gene expressions should influence awareness of and current recommendations for the management of these aggressive cancers.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0002-9610
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
177
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-8
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:10037301-Cyclin-Dependent Kinase Inhibitor p16,
pubmed-meshheading:10037301-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:10037301-Genetic Predisposition to Disease,
pubmed-meshheading:10037301-Germ-Line Mutation,
pubmed-meshheading:10037301-Humans,
pubmed-meshheading:10037301-Melanoma,
pubmed-meshheading:10037301-Mutation,
pubmed-meshheading:10037301-Pancreatic Neoplasms,
pubmed-meshheading:10037301-Prognosis,
pubmed-meshheading:10037301-Risk,
pubmed-meshheading:10037301-Skin Neoplasms
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pubmed:year |
1999
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pubmed:articleTitle |
Impact of p16 expression on surgical management of malignant melanoma and pancreatic carcinoma.
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pubmed:affiliation |
Department of Surgery, Medical University of South Carolina, Charleston 29425, USA.
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pubmed:publicationType |
Journal Article,
Review
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