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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1977-2-16
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pubmed:abstractText |
Invasive adenocarcinoma of the glandular stomach was induced in 3 BIO 87.20 inbred Syrian hamsters by the administration of 1 ppm N-nitrosodiethylamine or N-nitrosodimethylamine in the drinking water, and in 2 BIO 15.16 and 5 BIO 72.29 inbred Syrian hamsters by gavage of 3-methylcholanthrene. In contrast, many other similarly treated inbred Syrian hamster lines did not develop carcinoma of the glandular stomach. The glandular stomachs of rats and mice are resistant to polycyclic hydrocarcon carcinogenesis; however, the glandular stomachs of certain inbred Syrian hamsters develop adenocarcinoma after polycyclic hydrocarbon gavage. This work demonstrated the importance of genetic factors.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0027-8874
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
141-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1003497-Adenocarcinoma,
pubmed-meshheading:1003497-Animals,
pubmed-meshheading:1003497-Cricetinae,
pubmed-meshheading:1003497-Diethylnitrosamine,
pubmed-meshheading:1003497-Dimethylnitrosamine,
pubmed-meshheading:1003497-Female,
pubmed-meshheading:1003497-Male,
pubmed-meshheading:1003497-Mesocricetus,
pubmed-meshheading:1003497-Methylcholanthrene,
pubmed-meshheading:1003497-Neoplasms, Experimental,
pubmed-meshheading:1003497-Nitrosamines,
pubmed-meshheading:1003497-Species Specificity,
pubmed-meshheading:1003497-Stomach Neoplasms
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pubmed:year |
1976
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pubmed:articleTitle |
Adenocarcinoma of the glandular stomach following 3-methylcholanthrene, N-nitrosodiethylamine, or N-nitrosodimethylamine feeding in carcinogen-susceptible inbred Syrian.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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