rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1999-4-16
|
pubmed:abstractText |
A phospholipid, lysophosphatidylcholine (LPC), is the major determinant of the atherosclerotic properties of oxidized low-density lipoprotein (LDL). Under normal circumstances most LPC is bound to albumin. We hypothesized that lipoprotein LPC concentrations are increased in hypoalbuminemic patients with the nephrotic syndrome, irrespective of their lipid levels. To test this hypothesis, we selected nephrotic and control subjects with matched LDL cholesterol levels.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0085-2538
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
55
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1005-10
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10027937-Adolescent,
pubmed-meshheading:10027937-Adult,
pubmed-meshheading:10027937-Aged,
pubmed-meshheading:10027937-Cardiovascular Diseases,
pubmed-meshheading:10027937-Case-Control Studies,
pubmed-meshheading:10027937-Cholesterol,
pubmed-meshheading:10027937-Female,
pubmed-meshheading:10027937-Humans,
pubmed-meshheading:10027937-Hyperlipidemias,
pubmed-meshheading:10027937-Lipoproteins,
pubmed-meshheading:10027937-Lipoproteins, IDL,
pubmed-meshheading:10027937-Lipoproteins, LDL,
pubmed-meshheading:10027937-Lipoproteins, VLDL,
pubmed-meshheading:10027937-Lysophosphatidylcholines,
pubmed-meshheading:10027937-Male,
pubmed-meshheading:10027937-Middle Aged,
pubmed-meshheading:10027937-Nephrotic Syndrome,
pubmed-meshheading:10027937-Protein Binding,
pubmed-meshheading:10027937-Serum Albumin
|
pubmed:year |
1999
|
pubmed:articleTitle |
Hypoalbuminemia increases lysophosphatidylcholine in low-density lipoprotein of normocholesterolemic subjects.
|
pubmed:affiliation |
Department of Nephrology and Hypertension, Utrecht University, Utrecht, The Netherlands.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|