|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9146
|
|
pubmed:dateCreated |
1999-3-4
|
|
pubmed:abstractText |
Patients with the inherited disorder ataxia telangiectasia (A-T) have an increased susceptibility to lymphoid malignancies. In these patients mutations affect both alleles of the A-T gene (ATM). We have looked for mutations in the ATM gene in sporadic cases of B-cell chronic lymphocytic leukaemia (B-CLL).
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0140-6736
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
2
|
|
pubmed:volume |
353
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
26-9
|
|
pubmed:dateRevised |
2009-9-29
|
|
pubmed:meshHeading |
pubmed-meshheading:10023947-Alleles,
pubmed-meshheading:10023947-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:10023947-Ataxia Telangiectasia,
pubmed-meshheading:10023947-Blotting, Western,
pubmed-meshheading:10023947-Chromosomes, Human, Pair 11,
pubmed-meshheading:10023947-Cyclophosphamide,
pubmed-meshheading:10023947-DNA Fingerprinting,
pubmed-meshheading:10023947-DNA Restriction Enzymes,
pubmed-meshheading:10023947-Doxorubicin,
pubmed-meshheading:10023947-Female,
pubmed-meshheading:10023947-Genetic Predisposition to Disease,
pubmed-meshheading:10023947-Heterozygote,
pubmed-meshheading:10023947-Humans,
pubmed-meshheading:10023947-Leukemia, B-Cell,
pubmed-meshheading:10023947-Male,
pubmed-meshheading:10023947-Mutation,
pubmed-meshheading:10023947-Prednisolone,
pubmed-meshheading:10023947-Tandem Repeat Sequences,
pubmed-meshheading:10023947-Vincristine
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia.
|
|
pubmed:affiliation |
CRC Institute for Cancer Studies, Medical School, University of Birmingham, Edgbaston, UK.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
