Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1977-1-3
|
pubmed:abstractText |
The structure of polyguanylic acid (poly G) at neutral pH has been studied by optical and calorimetrical methods. It can be shown that diverging from earlier findings Poly G reversibly undergoes a cooperative thermal transition. Thermal denaturation curves are recorded at 253 nm as a function of the sodium ion concentration. The denaturation enthalpy of poly G in dilute aqueous solution is determined to 2.2 kcal/mole g. It is concluded, that the part of the ordered poly G structure, which gives rise to a temperature dependent cooperative transition, arises from stacking interactions of adjacent bases in the single strand.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0301-4622
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
5
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
359-61
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:10020-Calorimetry,
pubmed-meshheading:10020-Hot Temperature,
pubmed-meshheading:10020-Hydrogen-Ion Concentration,
pubmed-meshheading:10020-Kinetics,
pubmed-meshheading:10020-Molecular Weight,
pubmed-meshheading:10020-Nucleic Acid Conformation,
pubmed-meshheading:10020-Poly G,
pubmed-meshheading:10020-Polyribonucleotides,
pubmed-meshheading:10020-Thermodynamics
|
pubmed:year |
1976
|
pubmed:articleTitle |
A calorimetric study of polyguanylic acid at neutral pH.
|
pubmed:publicationType |
Journal Article
|