Linked Life Data

JAK-STAT cascade involved in growth hormone signaling pathway

Source:http://linkedlifedata.com/resource/geneontology/id/GO:0060397

Statements in which the resource exists as a subject.
PredicateObject
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skos:definition
"The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes." [GOC:BHF, GOC:dph, PMID:11445442]
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JAK-STAT cascade involved in growth hormone signaling pathway
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JAK-STAT cascade involved in growth hormone signalling pathway
skos:notation
Reactome:REACT_111133 "Growth hormone receptor signaling, Homo sapiens"
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