Source:http://linkedlifedata.com/resource/geneontology/id/GO:0051400
Predicate | Object |
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rdf:type | |
skos:definition |
"Interacting selectively and non-covalently with the Bcl-2 homology (BH) domain of a protein. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains." [PMID:11048732, PMID:12133724, PMID:9020082, PMID:9704409]
|
skos:inScheme | |
skos:prefLabel |
BH domain binding
|
skos:altLabel |
Bcl-2 homology domain binding
|
skos:broader |