Source:http://linkedlifedata.com/resource/geneontology/id/GO:0035195
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression." [PMID:14744438, PMID:15066275, PMID:15066283]
|
| skos:inScheme | |
| skos:prefLabel |
gene silencing by miRNA
|
| skos:altLabel |
gene silencing by microRNA,
miRNA-mediated gene silencing,
microRNA-mediated gene silencing
|
| skos:broader |