Source:http://linkedlifedata.com/resource/geneontology/id/GO:0017113
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+." [EC:1.3.1.2]
|
| skos:inScheme | |
| skos:prefLabel |
dihydropyrimidine dehydrogenase (NADP+) activity
|
| skos:altLabel |
4,5-dihydrothymine: oxidoreductase activity,
5,6-dihydrouracil:NADP+ 5-oxidoreductase activity,
DHU dehydrogenase activity,
dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate),
dihydropyrimidine dehydrogenase activity,
dihydrouracil dehydrogenase (NADP),
dihydrouracil dehydrogenase (NADP+) activity,
hydropyrimidine dehydrogenase activity
|
| skos:notation |
EC:1.3.1.2,
MetaCyc:1.3.1.2-RXN,
RHEA:18096,
Reactome:REACT_100185 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Bos taurus",
Reactome:REACT_101500 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Drosophila melanogaster",
Reactome:REACT_102325 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Escherichia coli",
Reactome:REACT_102503 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Caenorhabditis elegans",
Reactome:REACT_102856 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Oryza sativa",
Reactome:REACT_104406 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Xenopus tropicalis",
Reactome:REACT_104716 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Dictyostelium discoideum",
Reactome:REACT_104929 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Canis familiaris",
Reactome:REACT_1067 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Homo sapiens",
Reactome:REACT_106968 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Rattus norvegicus",
Reactome:REACT_107377 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Gallus gallus",
Reactome:REACT_107631 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Mus musculus",
Reactome:REACT_28626 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Danio rerio",
Reactome:REACT_29373 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Bos taurus",
Reactome:REACT_31473 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Danio rerio",
Reactome:REACT_33387 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Escherichia coli",
Reactome:REACT_546 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Homo sapiens",
Reactome:REACT_78060 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Xenopus tropicalis",
Reactome:REACT_80344 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Dictyostelium discoideum",
Reactome:REACT_80891 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Caenorhabditis elegans",
Reactome:REACT_81619 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Sus scrofa",
Reactome:REACT_85525 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Arabidopsis thaliana",
Reactome:REACT_85843 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Rattus norvegicus",
Reactome:REACT_86765 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Gallus gallus",
Reactome:REACT_87828 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Taeniopygia guttata",
Reactome:REACT_88182 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Mus musculus",
Reactome:REACT_89315 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Canis familiaris",
Reactome:REACT_89636 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Oryza sativa",
Reactome:REACT_92348 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Arabidopsis thaliana",
Reactome:REACT_92956 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Sus scrofa",
Reactome:REACT_95786 "thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+, Taeniopygia guttata",
Reactome:REACT_98344 "uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+, Drosophila melanogaster"
|
| skos:broader | |
| skos:relatedSynonym |
DPD,
DHPDH,
dihydrothymine dehydrogenase activity
|