Source:http://linkedlifedata.com/resource/geneontology/id/GO:0008282
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rdf:type | |
skos:definition |
"A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.2 subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SUR1 subunit stimulates channel activity." [PMID:16308567, PMID:16956886]
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skos:inScheme | |
skos:prefLabel |
ATP-sensitive potassium channel complex
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skos:broader |