farnesyl-diphosphate farnesyltransferase activity

Source:http://linkedlifedata.com/resource/geneontology/id/GO:0004310

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
skos:definition
"Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate." [EC:2.5.1.21]
skos:inScheme
skos:prefLabel
farnesyl-diphosphate farnesyltransferase activity
skos:altLabel
farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase activity, presqualene synthase activity, presqualene-diphosphate synthase activity
skos:notation
EC:2.5.1.21, MetaCyc:2.5.1.21-RXN, Reactome:REACT_101662 "Two FPP molecules dimerize to form presqualene diphosphate, Canis familiaris", Reactome:REACT_105154 "Two FPP molecules dimerize to form presqualene diphosphate, Danio rerio", Reactome:REACT_106161 "Reduction of presqualene diphosphate to form squalene, Danio rerio", Reactome:REACT_107400 "Two FPP molecules dimerize to form presqualene diphosphate, Oryza sativa", Reactome:REACT_108729 "Reduction of presqualene diphosphate to form squalene, Canis familiaris", Reactome:REACT_108746 "Reduction of presqualene diphosphate to form squalene, Mus musculus", Reactome:REACT_110869 "Reduction of presqualene diphosphate to form squalene, Oryza sativa", Reactome:REACT_112589 "Two FPP molecules dimerize to form presqualene diphosphate, Xenopus tropicalis", Reactome:REACT_112901 "Reduction of presqualene diphosphate to form squalene, Xenopus tropicalis", Reactome:REACT_29867 "Reduction of presqualene diphosphate to form squalene, Bos taurus", Reactome:REACT_77262 "Two FPP molecules dimerize to form presqualene diphosphate, Schizosaccharomyces pombe", Reactome:REACT_79816 "Reduction of presqualene diphosphate to form squalene, Gallus gallus", Reactome:REACT_80102 "Two FPP molecules dimerize to form presqualene diphosphate, Arabidopsis thaliana", Reactome:REACT_80447 "Reduction of presqualene diphosphate to form squalene, Rattus norvegicus", Reactome:REACT_80862 "Reduction of presqualene diphosphate to form squalene, Arabidopsis thaliana", Reactome:REACT_86856 "Two FPP molecules dimerize to form presqualene diphosphate, Mus musculus", Reactome:REACT_87065 "Reduction of presqualene diphosphate to form squalene, Dictyostelium discoideum", Reactome:REACT_89846 "Two FPP molecules dimerize to form presqualene diphosphate, Rattus norvegicus", Reactome:REACT_91748 "Two FPP molecules dimerize to form presqualene diphosphate, Bos taurus", Reactome:REACT_93117 "Two FPP molecules dimerize to form presqualene diphosphate, Dictyostelium discoideum", Reactome:REACT_93181 "Two FPP molecules dimerize to form presqualene diphosphate, Saccharomyces cerevisiae", Reactome:REACT_93268 "Two FPP molecules dimerize to form presqualene diphosphate, Taeniopygia guttata", Reactome:REACT_9504 "Reduction of presqualene diphosphate to form squalene, Homo sapiens", Reactome:REACT_9512 "Two FPP molecules dimerize to form presqualene diphosphate, Homo sapiens", Reactome:REACT_95255 "Reduction of presqualene diphosphate to form squalene, Schizosaccharomyces pombe", Reactome:REACT_96060 "Reduction of presqualene diphosphate to form squalene, Saccharomyces cerevisiae", Reactome:REACT_98548 "Reduction of presqualene diphosphate to form squalene, Taeniopygia guttata", Reactome:REACT_99523 "Two FPP molecules dimerize to form presqualene diphosphate, Gallus gallus"
skos:note
Note that the two reactions performed by EC:2.5.1.21 are represented in GO by 'farnesyl-diphosphate farnesyltransferase activity ; GO:0004310' and 'squalene synthase activity ; GO:0051996'.
skos:broader