Predicate | Object |
---|---|
rdf:type | |
entrezgene:geneRifText |
NAD+ levels cycle, driven by circadian clock; CLOCK:BMAL1 regulates circadian expression of NAMPT, an enzyme providing rate-limiting step in NAD+ salvage pathway; SIRT1 is recruited to Nampt promoter; NAMPT required to modulate circadian gene expression
|