| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:geneRifText |
Two evolutionarily conserved domains of MCAF1 directly interact with Sp1 and the general transcriptional apparatus. Selective depletion of MCAF1 or Sp1 down-regulates TERT and TERC genes in cultured cells, which results in decreased telomerase activity.
|