Source:http://linkedlifedata.com/resource/entrezgene/interaction/3565-155971
| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
Antigen-induced interleukin 4 secretion is markedly reduced in HIV-1 gp120-treated T cells,
HIV-1 gp120 cooperates with BAFF and cytokines IL-4 and IL-10 to activate mannose C-type lectin receptors-expressing B cells,
HIV-1 gp120 upregulates IL-4-induced IgE production through the regulation of the nitric oxide pathway,
Molecular interactions of CD2 with LFA-3 and CD28 with B7-1 in conjunction with TCR occupancy prevent T cells from programmed apoptosis mediated by binding of CD4 to HIV-1 gp120, resulting in increased levels of IL-2 and IL-4 secretion from the T cells,
Pretreatment of CD4+ cells with HIV-1 gp160 significantly reduces PHA-induced secretion of IFN-gamma and IL-2 but augments IL-4 production
|
| entrezgene:keyphrase |
downregulates,
interacts with,
cooperates with,
upregulates
|