Source:http://www4.wiwiss.fu-berlin.de/dailymed/resource/drugs/489
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:label |
EURAX (Cream)
|
| dailymed-instance:dosage |
In Scabies: Thoroughly massage into the skin
of the whole body from the chin down, paying particular attention to all folds
and creases. A second application is advisable 24 hours later. Clothing and
bed linen should be changed the next morning. A cleansing bath should be taken
48 hours after the last application. In Pruritus: Massage gently into affected areas
until medication is completely absorbed. Repeat as needed. LOTION: Shake well before using. DIRECTIONS FOR PATIENTS WITH SCABIES:
|
| dailymed-instance:descripti... |
Eurax (crotamiton USP) is a scabicidal and antipruritic agent available
as a cream or lotion for topical use only. Eurax provides 10% (w/w) of the
synthetic, crotamiton USP, in a vanishing-cream or emollient-lotion base containing:
carbomer-934, cetyl alcohol, diazolidinylurea, dimethicone, fragrance, laureth-23,
magnesium aluminum silicate, magnesium nitrate, methylchloroisothiazolinone,
methylisothiazolinone, petrolatum, propylene glycol, sodium hydroxide, steareth-2,
and water. In addition, the cream contains glyceryl stearate. Crotamiton is
N-ethyl-N-(o-methylphenyl)-2-butenamide and its structural
formula is: Crotamiton USP is a colorless to slightly yellowish oil, having
a faint amine-like odor. It is miscible with alcohol and with methanol. Crotamiton
is a mixture of the cis and trans isomers.
Its molecular weight is 203.28.
|
| dailymed-instance:clinicalP... |
Eurax has scabicidal and antipruritic actions. The mechanisms of
these actions are not known. The pharmacokinetics of crotamiton and its degree
of systemic absorption following topical application have not been determined.
|
| dailymed-instance:activeIng... | |
| dailymed-instance:contraind... |
Eurax should not be applied topically to patients who develop a
sensitivity or are allergic to it or who manifest a primary irritation response
to topical medications.
|
| dailymed-instance:supply |
Eurax (crotamiton USP) Store at room temperature. Keep out of reach of children.
|
| dailymed-instance:genericDr... | |
| dailymed-instance:activeMoi... | |
| dailymed-instance:inactiveI... |
dailymed-ingredient:carbomer-934,
dailymed-ingredient:cetyl_alcohol,
dailymed-ingredient:diazolidinylurea,
dailymed-ingredient:dimethicone,
dailymed-ingredient:fragrance,
dailymed-ingredient:glyceryl_stearate,
dailymed-ingredient:laureth-23,
dailymed-ingredient:magnesium_aluminum_silicate,
dailymed-ingredient:magnesium_nitrate,
dailymed-ingredient:methylchloroisothiazolinone,
dailymed-ingredient:methylisothiazolinone,
dailymed-ingredient:petrolatum,
dailymed-ingredient:propylene_glycol,
dailymed-ingredient:sodium_hydroxide,
dailymed-ingredient:steareth-2,
dailymed-ingredient:water
|
| dailymed-instance:precautio... |
General: Eurax should not be applied in the eyes or mouth because it may
cause irritation. It should not be applied to acutely inflamed skin or raw
or weeping surfaces until the acute inflammation has subsided.<br/>Information for Patients: See DIRECTIONS FOR PATIENTS WITH SCABIES.<br/>Drug Interactions: None known.<br/>Carcinogenesis, Mutagenesis, Impairment of Fertility: Long-term carcinogenicity studies in animals have not been conducted.<br/>Pregnancy (Category C): Animal reproduction studies have not been conducted with Eurax.
It is also not known whether Eurax can cause fetal harm when applied topically
to a pregnant woman or can affect reproduction capacity. Eurax should be given
to a pregnant woman only if clearly needed.<br/>Pediatric Use: Safety and effectiveness in pediatric patients have not been established.<br/>Geriatric Use: Clinical studies with Eurax (crotamiton USP) Lotion/Cream did not
include sufficient numbers of subjects aged 65 years and older to determine
whether they respond differently than younger subjects. Other reported clinical
experience has not identified differences in responses between elderly and
younger patients, but greater sensitivity of some older individuals cannot
be ruled out.
|
| dailymed-instance:overdosag... |
There is no specific information on the effect of overtreatment
with repeated topical applications in humans. A death was reported but cause
was not confirmed. Accidental oral ingestion may be accompanied by burning sensation
in the mouth, irritation of the buccal, esophageal and gastric mucosa, nausea,
vomiting, abdominal pain. If accidental ingestion occurs, call your Poison Control Center.
|
| dailymed-instance:genericMe... |
CROTAMITON
|
| dailymed-instance:fullName |
EURAX (Cream)
|
| dailymed-instance:adverseRe... |
Primary irritation reactions, such as dermatitis, pruritus, and
rash, and allergic sensitivity reactions have been reported in a few patients.
|
| dailymed-instance:warning |
If severe irritation or sensitization develops, treatment with
this product should be discontinued and appropriate therapy instituted.
|
| dailymed-instance:indicatio... |
For eradication of scabies (Sarcoptes scabiei) and
for symptomatic treatment of pruritic skin.
|
| dailymed-instance:represent... | |
| dailymed-instance:routeOfAd... | |
| dailymed-instance:name |
EURAX
|