Dexchlorpheniramine Maleate (Solution)

Source:http://www4.wiwiss.fu-berlin.de/dailymed/resource/drugs/382

Statements in which the resource exists as a subject.
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Dexchlorpheniramine Maleate (Solution)
dailymed-instance:dosage
DOSAGE SHOULD BE INDIVIDUALIZED ACCORDING TO THE NEEDS AND THE RESPONSE OF THE PATIENT.<br/>Recommended Dosage: Adults and Children 12 years of age and older: 2 mg (1 teaspoonful)Children 6 to 11 years: 1 mg (1/2 teaspoonful)Children 2 to 5 years: 0.5 mg (1/4 teaspoonful) Doses are generally given every 4 to 6 hours.
dailymed-instance:descripti...
Each 5 mL (teaspoonful) contains: Dexchlorpheniramine Maleate, USP. . . . . . . . . . . . . . . 2 mgAlcohol . . . . . . . . . . . . . . . . . . . . . . . . . not more than 7.0% Dexchlorpheniramine Maleate, USP, an antihistamine agent, is a white, odorless crystalline powder that is freely soluble in water. The molecular formula is CHClN���CHO, designated chemically as (+)-2-[p-Chloro-��-[2-(dimethylamino)ethyl]benzyl]pyridine maleate (1:1). Inactive Ingredients: Citric Acid; Dehydrated Alcohol; FD&C Red No. 40; Glycerin; Liquid Sugar; Menthol; Methylparaben; Natural and Artificial Orange Juice Flavor; Propylene Glycol; Propylparaben and Purified Water. May also contain Sodium Citrate for pH adjustment. The pH range is between 5.0 and 6.5.
dailymed-instance:clinicalP...
Dexchlorpheniramine maleate is an antihistamine with anticholinergic (drying) and sedative side effects. Antihistamines appear to compete with histamine for cell receptor sites on effector cells.
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Use in Newborn or Premature Infants: This drug should not be used in newborn or premature infants.<br/>Use in Nursing Mothers: Because of the higher risk of antihistamines for infants generally and for newborns and prematures in particular, antihistamine therapy is contraindicated in nursing mothers.<br/>Use in Lower Respiratory Disease: Antihistamines should NOT be used to treat lower respiratory tract symptoms including asthma. Antihistamines are also contraindicated in the following conditions:
dailymed-instance:supply
Dexchlorpheniramine Maleate Oral Solution, USP 2 mg/5 mL is supplied as a red-orange colored, orange flavored liquid in the following sizes: 4 fl oz (118 mL)16 fl oz (473 mL)128 fl oz (3785 mL)<br/>RECOMMENDED STORAGE: Store at 20�����25��C (68�����77��F) [See USP Controlled Room Temperature]. Dispense in a tight, light-resistant container as defined in the USP, with child-resistant closure.
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dailymed-instance:precautio...
Dexchlorpheniramine Maleate, USP has an atropine-like action and, therefore, should be used with caution in patients with:<br/>Drug Interaction: MAO inhibitors prolong and intensify the anticholinergic (drying) effects of antihistamines.
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Dexchlorpheniramine Maleate
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Dexchlorpheniramine Maleate (Solution)
dailymed-instance:warning
Antihistamines should be used with considerable caution in patients with:<br/>Use in Children: In infants and children, especially, antihistamines in overdosage may cause hallucinations, convulsions, or death. As in adults, antihistamines may diminish mental alertness in children. In the young child, particularly, they may produce excitation.<br/>Use in Pregnancy: Experience with this drug in pregnant women is inadequate to determine whether there exists a potential for harm to the developing fetus.<br/>Use with CNS Depressants: Dexchlorpheniramine Maleate, USP has additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, etc.).<br/>Use in Activities Requiring Mental Alertness: Patients should be warned about engaging in activities requiring mental alertness such as driving a car or operating appliances, machinery, etc.<br/>Use in the Elderly (approximately 60 years or older): Antihistamines are more likely to cause dizziness, sedation, and hypotension in elderly patients.
dailymed-instance:indicatio...
Perennial and seasonal allergic rhinitisVasomotor rhinitisAllergic conjunctivitis due to inhalant allergens and foodsMild, uncomplicated allergic skin manifestations of urticaria and angioedemaAmelioration of allergic reactions to blood or plasmaDermographism As therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled.
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Dexchlorpheniramine Maleate