Source:http://www4.wiwiss.fu-berlin.de/dailymed/resource/drugs/3773
| Subject | Predicate | Object | Context |
|---|---|---|---|
| dailymed-drugs:3773 | rdf:type | http://www4.wiwiss.fu-berli... | lld:dailymed |
| dailymed-drugs:3773 | rdf:type | dailymed-instance:drugs | lld:dailymed |
| dailymed-drugs:3773 | rdfs:label | Acetic Acid (Irrigant) | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:dosage | As required for urologic irrigation. 0.25% Acetic Acid Irrigation USP may be administered by gravity drip via an administration set connected to an indwelling urethral catheter designed for continuous or intermittent two-way flow. For continuous or intermittent irrigation, the rate of administration will correspond roughly to the rate of urine flow and should be adjusted to maintain a urinary effluent pH of 4.5 to 5.0. Nitrazine or other pH paper may be used to monitor pH, preferably at least four times daily. Drip rate should be adjusted as necessary to maintain desired pH; increasing flow rate reduces pH value and vice versa. With continuous or intermittent irrigation, each patient will require a volume of approximately 500 to 1500 mL per 24 hours. Some additives may be incompatible. Consult with pharmacist. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. This drug product should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:descripti... | Each 100 mL contains: Glacial Acetic Acid USP 0.25 gWater for Injection USP qs pH: 3.1 (2.8���3.4)Calculated Osmolarity: 42 mOsmol/liter The formula of the active ingredient is: Ingredient Molecular Formula Molecular Weight Glacial Acetic Acid USP CHCOOH 60.05 0.25% Acetic Acid Irrigation USP is a prediluted, sterile, nonpyrogenic aqueous solution suitable for urologic irrigation. It contains no preservatives or added buffers. The solution is hypotonic. The plastic container is a copolymer of ethylene and propylene formulated and developed for parenteral drugs. The copolymer contains no plasticizers and exhibits virtually no leachability. The plastic container is also virtually impermeable to vapor transmission and therefore, requires no overwrap to maintain the proper drug concentration. The safety of the plastic container has been confirmed by biological evaluation procedures. The material passes Class Vl testing as specified in the U.S. Pharmacopeia for Biological Tests���Plastic Containers. These tests have shown that the container is nontoxic and biologically inert. | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:clinicalP... | Irrigation of the urinary bladder with acetic acid solution in a concentration of 0.25% has been shown to exert an antimicrobial action against a variety of microorganisms (especially ammonia-forming bacteria) that frequently gain access to the urinary bladder in patients who require prolonged indwelling urethral catheterization. Its antimicrobial action is dependent on administration via the indwelling catheter at asufficient rate (continuous or intermittent) to maintain an effluent pH of 5.0 or lower. Maintenance of low pH of bladder urine also helps reduce formation of calcium encrustations in the indwelling catheter. | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:activeIng... | dailymed-ingredient:Acetic_... | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:contraind... | 0.25% Acetic Acid Irrigation USP is not for injection. This solution is contraindicated for irrigation during transurethral surgical procedures. | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:supply | 0.25% Acetic Acid Irrigation USP is supplied sterile and nonpyrogenic in 1000 mL and 500 mL PIC���(Plastic Irrigation Containers) packaged 16 per case. NDC Cat. No. Size 0.25% Acetic Acid Irrigation USP 0264-2304-00 R6600-01 1000 mL 0264-2304-10 R6601-01 500 mL Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. Protect from freezing. It is recommended that the product be stored at room temperature (25��C); however, brief exposure up to 40��C does not adversely affect the product. Do not warm above 150��F (66��C). | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:genericDr... | http://www4.wiwiss.fu-berli... | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:activeMoi... | dailymed-ingredient:Acetic_... | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:inactiveI... | dailymed-ingredient:Water | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:1025 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:79 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:1205 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:4188 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:516 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:614 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:631 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:633 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:1023 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:1428 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:2616 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:2617 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:2811 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:2835 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:2838 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:3833 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:3834 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:possibleD... | diseasome-diseases:3842 | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:overdosag... | Systemic absorption is unlikely unless there are open lesions of the bladder mucosa that have gone undetected. In such event, discontinue the irrigation, evaluate the patient for possible systemic acidosis, intravascular hemolysis, and circulatory overload and institute appropriate countermeasures as indicated. See WARNINGS, PRECAUTIONS, and ADVERSE REACTIONS. | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:genericMe... | Acetic Acid | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:fullName | Acetic Acid (Irrigant) | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:adverseRe... | Systemic acidosis, pain, and hematuria have been reported in patients receiving urinary bladder irrigation with 0.25% acetic acid solution. If an adverse reaction does occur, discontinue administration of the irrigant, evaluate the patient, institute appropriate therapeutic countermeasures, and save the remainder of the fluid for examination, if deemed necessary. | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:indicatio... | 0.25% Acetic Acid Irrigation USP is indicated as a constant or intermittent bladder rinse to help prevent the growth and proliferation of susceptible urinary pathogens (especially ammonia-forming bacteria) in the management of patients who require prolonged placement of an indwelling urethral catheter. It also may be used for periodic irrigation of an indwelling catheter to help maintain patency by reducing the formation of calcium encrustations. | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:represent... | http://www4.wiwiss.fu-berli... | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:routeOfAd... | http://www4.wiwiss.fu-berli... | lld:dailymed |
| dailymed-drugs:3773 | dailymed-instance:name | Acetic Acid | lld:dailymed |
| http://www4.wiwiss.fu-berli... | dailymed-instance:producesD... | dailymed-drugs:3773 | lld:dailymed |
| diseasome-diseases:1025 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:79 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:1205 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:4188 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:516 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:614 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:631 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:633 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:1023 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:1428 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:2616 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:2617 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:2811 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:2835 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:2838 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:3833 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:3834 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |
| diseasome-diseases:3842 | diseasome-instance:possible... | dailymed-drugs:3773 | lld:diseasome |