Statements in which the resource exists as a subject.
PredicateObject
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Stavudine (Capsule)
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Dosage Adjustment:
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Special Populations:<br/>Drug Interactions:
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Stavudine capsules are contraindicated in patients with clinically significant hypersensitivity to stavudine or to any of the components contained in the formulation.
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WARNING:
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Fat Redistribution:<br/>Information for Patients:<br/>Drug Interactions:<br/>Carcinogenesis, Mutagenesis, Impairment of Fertility:<br/>Pregnancy:<br/>Teratogenic Effects:<br/>Nursing Mothers: The Centers for Disease Control and Prevention recommend that HIV-infected mothers not breast-feed their infants to avoid risking postnatal transmission of HIV. Studies in lactating rats demonstrated that stavudine is excreted in milk. Although it is not known whether stavudine is excreted in human milk, there exists the potential for adverse effects from stavudine in nursing infants. Because of both the potential for HIV transmission and the potential for serious adverse reactions in nursing infants, mothers should be instructed not to breast-feed if they are receiving stavudine.<br/>Pediatric Use:<br/>Geriatric Use:
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Experience with adults treated with 12 to 24 times the recommended daily dosage revealed no acute toxicity. Complications of chronic overdosage include peripheral neuropathy and hepatic toxicity. Stavudine can be removed by hemodialysis; the mean��SD hemodialysis clearance of stavudine is 120��18 mL/min. Whether stavudine is eliminated by peritoneal dialysis has not been studied.
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Stavudine
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Stavudine (Capsule)
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3. Neurologic Symptoms:
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CLINICAL STUDIES:
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dailymed-instance:name
Stavudine