Source:http://www4.wiwiss.fu-berlin.de/dailymed/resource/drugs/3234
Predicate | Object |
---|---|
rdf:type | |
rdfs:label |
CARBATROL Extended-Release (Capsule, Extended Release)
|
dailymed-instance:dosage |
Monitoring of blood levels has increased the efficacy and safety
of anticonvulsants (see PRECAUTIONS,
Laboratory Tests). Dosage should be adjusted to the needs
of the individual patients. A low initial daily dosage with gradual
increase is advised. As soon as adequate control is achieved, the dosage
may be reduced very gradually to the minimumeffective level. The
Carbatrol capsules may be opened and the beads sprinkled over food, such
as a teaspoon of applesauce or other similar food products if this
method of administration is preferred. Carbatrol capsules or their
contents should not be crushed or chewed. Carbatrol can be taken with or
without meals. Carbatrol is an extended-release formulation for twice a day
administration. When converting patients from immediate release
carbamazepine to Carbatrol extended-release capsules, the same total
daily mg dose of carbamazepine should be administered.<br/>Epilepsy (see INDICATIONS AND USAGE): Adults and children over 12
years of age. Initial: 200 mg twice daily.
Increase at weekly intervals by adding up to 200 mg/day until
the optimal response is obtained. Dosage generally should not
exceed 1000 mg per day in children 12-15 years of age, and 1200
mg daily in patients above 15 years of age. Doses up to 1600 mg
daily have been used in adults. Maintenance: Adjust dosage to the minimum
effective level, usually 800-1200 mg daily. Children under 12 years of
age: Children taking total daily dosages of
immediate-release carbamazepine of 400 mg or greater may be
converted to the same total daily dosage of Carbatrol
extended-release capsules, using a twice daily regimen.
Ordinarily, optimal clinical response is achieved at daily doses
below 35 mg/kg. If satisfactory clinical response has not been
achieved, plasma levels should be measured to determine whether
or not they are in the therapeutic range. No recommendation
regarding the safety of Carbatrol for use at doses above 35
mg/kg/24 hours can be made. Combination Therapy:
Carbatrol may be used alone or with other anticonvulsants. When
added to existing anticonvulsant therapy, the drug should be
added gradually while the other anticonvulsants are maintained
or gradually decreased, except phenytoin, which may have to be
increased (see PRECAUTIONS,
Drug Interactions, and Pregnancy
Category D).<br/>Trigeminal Neuralgia (see INDICATIONS AND USAGE): Initial: On the first day, start with one 200 mg capsule. This daily dose may be
increased by up to 200 mg/day every 12 hours only as needed to
achieve freedom from pain. Do not exceed 1200 mg daily. Maintenance: Control
of pain can be maintained in most patients with 400-800 mg
daily. However, some patients may be maintained on as little as
200 mg daily, while others may require as much as 1200 mg daily.
At least once every 3 months throughout the treatment period,
attempts should be made to reduce the dose to the minimum
effective level or even to discontinue the drug.
|
dailymed-instance:activeIng... | |
dailymed-instance:genericDr... | |
dailymed-instance:activeMoi... | |
dailymed-instance:inactiveI... |
dailymed-ingredient:FD&C_Blue_#2,
dailymed-ingredient:Yellow_Iron_Oxide,
dailymed-ingredient:citric_acid,
dailymed-ingredient:colloidal_silicon_dioxide,
dailymed-ingredient:gelatin,
dailymed-ingredient:lactose_monohydrate,
dailymed-ingredient:microcrystalline_cellulose,
dailymed-ingredient:polyethylene_glycol,
dailymed-ingredient:povidone,
dailymed-ingredient:sodium_lauryl_sulfate,
dailymed-ingredient:talc,
dailymed-ingredient:titanium_dioxide,
dailymed-ingredient:triethyl_citrate,
dailymed-ingredient:white_ink
|
dailymed-instance:possibleD... | |
dailymed-instance:genericMe... |
carbamazepine
|
dailymed-instance:fullName |
CARBATROL Extended-Release (Capsule, Extended Release)
|
dailymed-instance:indicatio... |
Epilepsy: Carbatrol is indicated for use as an anticonvulsant drug.
Evidence supporting efficacy of carbamazepine as an
anticonvulsant was derived from active drug-controlled studies
that enrolled patients with the following seizure types:<br/>Trigeminal Neuralgia: Carbatrol is indicated in the treatment of the pain
associated with true trigeminal neuralgia. Beneficial results
have also been reported in glossopharyngeal neuralgia. This drug
is not a simple analgesic and should not be used for the relief
of trivial aches or pains.
|
dailymed-instance:represent... | |
dailymed-instance:routeOfAd... | |
dailymed-instance:name |
CARBATROL Extended-Release
|