Source:http://www4.wiwiss.fu-berlin.de/dailymed/resource/drugs/223
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:label |
CARAFATE (Suspension)
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| dailymed-instance:dosage |
Active Duodenal Ulcer. The recommended adult oral dosage for duodenal ulcer is 1 g (10 mL/2 teaspoonfuls) four times per day. CARAFATE should be administered on an empty stomach. Antacids may be prescribed as needed for relief of pain but should not be taken within one-half hour before or after sucralfate. While healing with sucralfate may occur during the first week or two, treatment should be continued for 4 to 8 weeks unless healing has been demonstrated by x-ray or endoscopic examination.
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| dailymed-instance:clinicalP... |
Sucralfate is only minimally absorbed from the gastrointestinal tract. The small amounts of the sulfated disaccharide that are absorbed are
excreted primarily in the urine. Although the mechanism of sucralfate's ability to accelerate healing of duodenal ulcers remains to be fully defined, it is known that it exerts its effect through a local, rather than systemic, action. The following observations also appear pertinent: These observations suggest that sucralfate's antiulcer activity is the result of formation of an ulcer-adherent complex that covers the ulcer
site and protects it against further attack by acid, pepsin, and bile salts. There are approximately 14 to 16 mEq of acid-neutralizing capacity per 1-g
dose of sucralfate.
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| dailymed-instance:activeIng... | |
| dailymed-instance:supply |
CARAFATE (sucralfate) Suspension 1 g/10 mL is a pink suspension supplied in bottles of 14 fl oz (NDC 58914-170-14). SHAKE WELL BEFORE USING. Store at controlled room temperature 20-25��C (68-77��F)[see USP]. Rx Only Prescribing Information as of April 2004 Axcan Scandipharm Inc. 22 Inverness Center Parkway Birmingham, AL 35242 www.axcan.com
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| dailymed-instance:genericDr... | |
| dailymed-instance:activeMoi... | |
| dailymed-instance:inactiveI... |
dailymed-ingredient:FD&C_Red_#40,
dailymed-ingredient:colloidal_silicon_dioxide,
dailymed-ingredient:flavor,
dailymed-ingredient:glycerin,
dailymed-ingredient:methylcellulose,
dailymed-ingredient:methylparaben,
dailymed-ingredient:microcrystalline_cellulose,
dailymed-ingredient:simethicone,
dailymed-ingredient:sorbitol_solution,
dailymed-ingredient:water
|
| dailymed-instance:possibleD... |
diseasome-diseases:1130,
diseasome-diseases:1358,
diseasome-diseases:1359,
diseasome-diseases:1427,
diseasome-diseases:1436,
diseasome-diseases:2198,
diseasome-diseases:2202,
diseasome-diseases:2203,
diseasome-diseases:2204,
diseasome-diseases:2205,
diseasome-diseases:2730,
diseasome-diseases:338,
diseasome-diseases:342,
diseasome-diseases:4046,
diseasome-diseases:4047,
diseasome-diseases:46,
diseasome-diseases:576,
diseasome-diseases:79,
diseasome-diseases:81
|
| dailymed-instance:genericMe... |
sucralfate
|
| dailymed-instance:fullName |
CARAFATE (Suspension)
|
| dailymed-instance:adverseRe... |
Adverse reactions to sucralfate tablets in clinical trials were minor and only rarely led to discontinuation of the drug. In studies involving over 2700 patients treated with sucralfate, adverse effects were reported in 129 (4.7%). Constipation was the most frequent complaint (2%). Other adverse effects reported in less than 0.5% of the patients are listed below by body system: Gastrointestinal: diarrhea, dry mouth, flatulence, gastric discomfort, indigestion, nausea, vomiting Dermatological: pruritus, rash Nervous System: dizziness, insomnia, sleepiness, vertigo Other: back pain, headache Postmarketing reports of hypersensitivity reactions, including urticaria (hives), angioedema, respiratory difficulty, rhinitis, laryngospasm, and facial swelling have been reported in patients receiving sucralfate tablets. Similar events were reported with sucralfate suspension. However, a causal relationship has not been established. Bezoars have been reported in patients treated with sucralfate. The majority of patients had underlying medical conditions that may predispose to bezoar formation (such as delayed gastric emptying) or were receiving concomitant enteral tube feedings. Inadvertent injection of insoluble sucralfate and its insoluble excipients has led to fatal complications, including pulmonary and cerebral emboli. Sucralfate is not intended for intravenous administration.
|
| dailymed-instance:indicatio... |
CARAFATE (sucralfate) Suspension is indicated in the short-term (up to 8 weeks) treatment of active duodenal ulcer.
|
| dailymed-instance:represent... | |
| dailymed-instance:routeOfAd... | |
| dailymed-instance:name |
CARAFATE
|