Source:http://www4.wiwiss.fu-berlin.de/dailymed/resource/drugs/1742
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:label |
Ammonium Lactate (Cream)
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| dailymed-instance:dosage |
Apply to the affected areas and rub in thoroughly. Use twice daily or as directed by a physician.
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| dailymed-instance:descripti... |
Ammonium Lactate Cream, 12% is a formulation of 12% lactic acid neutralized with ammonium hydroxide, as ammonium lactate with a pH of 4.4 - 5.4. Ammonium Lactate Cream, 12% also contains water, light mineral oil, glyceryl stearate, PEG-100 stearate, propylene glycol, polyoxyl 40 stearate, glycerin, cetyl alcohol, magnesium aluminum silicate, polyoxyethylene 4 lauryl ether, methyl and propyl parabens, and methylcellulose. Lactic acid is a racemic mixture of 2-hydroxypropanoic acid and has the following structural formula:
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| dailymed-instance:clinicalP... |
Lactic acid is an alpha-hydroxy acid. It is a normal constituent of tissues and blood. The alpha-hydroxy acids (and their salts) are felt to act as humectants when applied to the skin. This property may influence hydration of the stratum corneum. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion. The mechanism(s) by which this is accomplished is not yet known. An in vitro study of percutaneous absorption of ammonium lactate cream using human cadaver skin indicates that approximately 6.1% of the material was absorbed after 68 hours.
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| dailymed-instance:activeIng... | |
| dailymed-instance:contraind... |
None known.
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| dailymed-instance:supply |
Ammonium lactate cream is available in cartons of 280 g (2-140 g plastic tubes). Store at controlled room temperature, 15��to 30��C (59��to 86��F).
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| dailymed-instance:activeMoi... | |
| dailymed-instance:inactiveI... |
dailymed-ingredient:PEG-100_stearate,
dailymed-ingredient:cetyl_alcohol,
dailymed-ingredient:glycerin,
dailymed-ingredient:glyceryl_stearate,
dailymed-ingredient:light_minera_oil,
dailymed-ingredient:magnesium_aluminum_silicate,
dailymed-ingredient:methylcellulose,
dailymed-ingredient:metyl_and_propyl_parabens,
dailymed-ingredient:polyoxyethylene_4_lauryl_ether,
dailymed-ingredient:polyoxyl_40_stearate,
dailymed-ingredient:propylene_gycol,
dailymed-ingredient:water
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| dailymed-instance:genericMe... |
Ammonium Lactate
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| dailymed-instance:fullName |
Ammonium Lactate (Cream)
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| dailymed-instance:adverseRe... |
In controlled clinical trials of patients with ichthyosis vulgaris, the most frequent adverse reactions in patients treated with ammonium lactate cream were rash (including erythema and irritation) and burning/stinging. Each was reported in approximately 10 - 15% of patients. In addition, itching was reported in approximately 5% of patients. In controlled clinical trials of patients with xerosis, the most frequent adverse reactions in patients treated with ammonium lactate cream were transient burning, in about 3% of patients, stinging, dry skin and rash, each reported in approximately 2% of patients.
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| dailymed-instance:represent... | |
| dailymed-instance:routeOfAd... | |
| dailymed-instance:name |
Ammonium Lactate
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