Source:http://www4.wiwiss.fu-berlin.de/dailymed/resource/drugs/1262
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:label |
Lactated Ringers (Irrigant)
|
| dailymed-instance:dosage |
The volume of
solution needed will vary with the nature and duration of the
arthroscopic procedure. If desired, warm in
overwrap to near body temperature in a water bath or oven heated to not
more than 45��C. Parenteral drug
products should be inspected visually for particulate matter and
discoloration prior to administration whenever solution and container
permit.
|
| dailymed-instance:descripti... |
Lactated Ringer's
Irrigation is a sterile, nonpyrogenic, isotonic solution in a single
dose ARTHROMATIC plastic container for use as an arthroscopic irrigating
solution. Each liter contains 6.0 g Sodium Chloride, USP, (NaCl), 3.1 g
Sodium Lactate (CHNaO), 300 mg
Potassium Chloride, USP, (KCl), and 200 mg Calcium Chloride, USP,
(CaCl���2HO). pH 6.5 (6.0 to 7.5).
Milliequivalents per liter: Sodium - 130, Potassium - 4, Calcium - 3,
Chloride - 109, Lactate - 28. Osmolarity 273 mOsmol/L (calc.). No
antimicrobial agent has been added. The ARTHROMATIC
plastic container is fabricated from a specially formulated polyvinyl
chloride (PL 146 Plastic). The amount of water that can permeate from
inside the container into the overwrap is insufficient to affect the
solution significantly. Solutions in contact with the plastic container can leach out certain of its chemical components in very small amounts
within the expiration period, e.g., di-2-ethylhexylphthalate (DEHP), up
to 5 parts per million. However, the safety of the plastic has been
confirmed in tests in animals according to USP biological tests for
plastic containers as well as by tissue culture toxicity
studies.
|
| dailymed-instance:clinicalP... |
Lactated Ringer's
Irrigation is useful as an irrigating fluid for body joints because it
approximates the electrolyte composition of synovial fluid, and provides
a transparent fluid medium with optical properties suitable for good
visualization of the interior joint surface during endoscopic
examination. During arthroscopic surgical procedures, the solution acts
as a lavage for removing blood, tissue fragments, and bone
fragments.
|
| dailymed-instance:activeIng... | |
| dailymed-instance:contraind... |
None
known.
|
| dailymed-instance:supply |
Lactated Ringer's
Irrigation in ARTHROMATIC Plastic Container is available as follows: Exposure of
pharmaceutical products to heat should be minimized. Avoid excessive
heat. It is recommended the product be stored at room temperature (25��C); brief exposure up to 40��C does not adversely affect the
product.
|
| dailymed-instance:activeMoi... | |
| dailymed-instance:inactiveI... | |
| dailymed-instance:precautio... |
Because some of the
fluid used to irrigate joints may be absorbed, caution must be exercised
in the volume of irrigating fluid used especially with solutions containing the sodium ion in patients receiving corticosteroids or
corticotropin.<br/>Pediatric Use: Safety and
effectiveness in pediatric patients have not been established. Do not
administer unless the solution is clear and the seal is
intact.
|
| dailymed-instance:genericMe... |
sodium chloride, soldium lactate, potassium chloride and calcium chloride
|
| dailymed-instance:fullName |
Lactated Ringers (Irrigant)
|
| dailymed-instance:adverseRe... |
None
known.
|
| dailymed-instance:warning |
Not for injection. Because fluids used
to irrigate joints may be absorbed into the general circulation,
solutions containing sodium ion should be used with great care in
patients with congestive heart failure, severe renal insufficiency, and
in clinical states in which there exists edema with sodium retention. The contents of an
opened container should be used promptly to minimize the possibility of
bacterial growth or pyrogen formation. Discard the unused portion of
irrigating solution since no antimicrobial agent has been
added.
|
| dailymed-instance:indicatio... |
Lactated Ringer's
Irrigation is indicated for use as an arthroscopic irrigating fluid with
endoscopic instruments during arthroscopic procedures requiring
distension and irrigation of the knee, shoulder, elbow, or other bone
joints.
|
| dailymed-instance:represent... | |
| dailymed-instance:routeOfAd... | |
| dailymed-instance:name |
Lactated Ringers
|